Use of mean platelet volume and platelet distribution width in predicting trend in platelet count and bleeding risks in patients of dengue fever

Authors

  • Prakash G. M. Department of Medicine, MIMS, Mandya, Karnataka, India
  • Anikethana G. V. Department of Medicine, MIMS, Mandya, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20162504

Keywords:

Dengue fever, Platelet count, MPV, PDW

Abstract

Background: Dengue fever is a global re-emerging disease. Various parameters have been used to predict the complications of the Dengue fever. MPV and PDW is used to predict the trend in the platelet count and risk of bleeding manifestations.

Methods: It is a prospective observational study at MIMS, Mandya. The patient’s data, platelet count, MPV, PDW and clinical characteristics were selected using standard proforma.

Results: Out of 15 patients with Dengue fever, only 2 patients had petechial rashes, There were no cases of DSS or DHF. There was no correlation between the platelet count, MPV, PDW, serology, gender and severity of the cases. There was no significant correlation between the Platelet count, MPV and PDW.

Conclusions: There was no correlation between the platelet count, MPV and PDW in patients with dengue fever.

References

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Oliveira EC, Pontes ER, Cunha RV, Fróes IB, Nascimento D. Hematological changes in patients with dengue. Rev. Soc. Bras. Med. Trop. 2009;42(6):682-5.

Bashir AB, Saeed OK, Mohammed BA, Ageep AK. Role of Platelet Indices in Patients with Dengue Infection in Red Sea State, Sudan. IJSR. 2015;4(1):l573-6.

Eldor A, Avitzour M, OR R, Hanna R, Penchas S. Prediction of haemorrhagic diathesis in thrombocytopenia by mean platelet volume. Br Med J. 1982;285(6339):397-400.

Dewi YP. Mean Platelet Volume (MPV): Potential Predictor of Disease Severity in Dengue infection. In proceeding of: International Dengue Symposium. 2013 conference paper.

Wiwanitkit V. Mean platelet volume in the patients with dengue hemorrhagic fever. Platelets. 2004;15(3):185.

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Published

2016-12-29

Issue

Section

Original Research Articles