A study of clinical profile of patients with chronic pulmonary obstructive disease at a tertiary care centre in North Karnataka, India

Authors

  • Ashok Kumar Gudagunti Department of Pulmonary Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka, India
  • Ishwar Hasabi Department of Pulmonary Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka, India
  • Arathy S. Department of Pulmonary Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20191074

Keywords:

Clinical profile, Co-morbidities, Hypertension, Patients, Symptoms

Abstract

Background: Chronic pulmonary obstructive disease (COPD) has been responsible for the decreased quality of life as well as increased morbidity and mortality. Globally it has been estimated that nearly three million die yearly due to COPD and more likely to occupy the third place of mortality by 2030. The objective of the present endeavour was to study clinical profile of patients with chronic pulmonary obstructive disease at a tertiary care centre.

Methods: A hospital based cross sectional study was carried out among 200 cases of COPD. Their detailed history, thorough clinical examination and parameters like hemoglobin, serum creatinine, protein etc were investigated. The presence of co-morbidities was noted.

Results: As the age increased the prevalence of the COPD increased and highest was found out to be in the age group of above 60 years of age. Males were more affected with COPD as compared with females. The male to female ratio was found out to be 2.4:1. The smokers were more compared to the non smokers. The prevalence of smoking among COPD was noted to be 66% compared to 34% as non smokers. Least proportion of patients of the COPD had fever i.e. in 22% of the cases. Cough was found in 83% of the cases. Breathlessness was found out to be in 98% of the cases. 15% of the cases of the COPD had diabetes only as the co-morbidity along with COPD and no other co-morbidity.

Conclusions: Breathlessness was the most common symptom at presentation and diabetes and hypertension were the most common co-morbidities found.

References

Jindal SK, Aggarwal AN, Gupta D et al. Indian study on epidemiology of asthma, respiratory symptoms and chronic bronchitis in adults (INSEARCH). Int J Tuberc Lung Dis. 2012 Sep;16;(9):1270-7.

Jindal SK. COPD: The Unrecognized Epidemic in India. Supplement to J Assoc Physicians India 2012;60:14-6.

de Marco R, Accordini S, Marcon A, Cerveri I, Antó JM, Gislason T, Heinrich J, Janson C, et al. Risk Factors for Chronic Obstructive Pulmonary Disease in a European Cohort of Young Adults. Am J Respir Crit Care Med. 2012;183:891-7.

Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, et al. An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Resp Critical Care Med. 2010 Sep 1;182(5):693-718.

Brashier BB, Kodgule R. Risk factors and pathophysiology of chronic obstructive pulmonary disease (COPD). J Assoc Physicians India. 2012 Feb;60(Suppl):17-21.

Paulin LM, Diette GB, Blanc PD, Putcha N, Eisner MD, Kanner RE, et al. Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Am J Resp Critical Care Med. 2015 Mar 1;191(5):557-65.

Pedone C, Scarlata S, Forastiere F, Bellia V, Antonelli Incalzi R. BODE index or geriatric multidimensional assessment for the prediction of very-long-term mortality in elderly patients with chronic obstructive pulmonary disease? A prospective cohort study. Age Ageing. 2013 Dec 12;43(4):553-8.

Ko FW, Tam W, Tung AH, Ngai J, Ng SS, Lai K, et al. A longitudinal study of serial BODE indices in predicting mortality and readmissions for COPD. Resp Med. 2011 Feb 1;105(2):266-73.

Celli BR. Predictors of mortality in COPD. Respiratory Med. 2010;104(6):773-9.

Gray-Donald K, Gibbons L, Shapiro SH, Macklem PT, Martin JG. Nutritional status and mortality in chronic obstructive pulmonary disease. Am J Resp Critical Care Med. 1996 Mar;153(3):961-6.

Marti S, Munoz X, Rios J, Morell F, Ferrer J. Body weight and comorbidity predict mortality in COPD patients treated with oxygen therapy. Eur Resp J. 2006 Apr 1;27(4):689-96.

Soriano JB, Lamprecht B, Ramírez AS, Martinez-Camblor P, Kaiser B, et al. Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2007 and 2011 staging systems: a pooled analysis of individual patient data. Lancet Resp Med. 2015 Jun 1;3(6):443-50.

Boutou AK, Shrikrishna D, Tanner RJ, Smith C, Kelly JL, Ward SP, et al. Lung function indices for predicting mortality in COPD. European Respiratory Journal. 2013 Sep 1;42(3):616-25.

Eagan TM, Ueland T, Wagner PD, Hardie JA, Mollnes TE, Damås JK, et al. Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study. Eur Resp J. 2010 Mar 1;35(3):540-8.

Soler-Cataluna JJ, Martínez-García MÁ, Sanchez PR, Salcedo E, Navarro M, Ochando R. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005 Nov 1;60(11):925-31.

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Published

2019-03-25

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Original Research Articles