DOI: http://dx.doi.org/10.18203/2349-3933.ijam20195258

Adult onset still’s disease: a diagnostic dilemma

Dugganapalli Dinesh Kumar Reddy, Veeraballi Sindhusha, Metta Jagadeesh

Abstract


Adult onset still’s disease is a rare systemic inflammatory disorder of unknown aetiology, characterized by clinical triad (high spiking fever, evanescent rash and arthritis) and biological triad with lack of serological markers as a true gold standard makes diagnosis difficulty. Here is a case of 32year old male presented with high grade fever for 2 months, joint pains and swelling for 1month rash for 3 days. O/E: pallor and B/L tender, swollen ankle and knee joints, and P/A: splenomegaly. Investigations showed-Hb%. 8 gms, neutrophilic leucocytosis with thrombocytosis, ESR:72 mm/1h, CRP elevated. ASO-titre, RA factor and Anti CCP antibodies are negative. Adult onset still’s disease is a heterogenous and rare systemic inflammatory disorder of unknown aetiology with lack of serological diagnostic modalities.


Keywords


Adult onset still’s disease, Arthritis, Evanescent rash, High spiking fever, Pyrexia of unknown origin

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References


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