Key points of cooperation for successful implementation of bedside TCD in brain death determination

Guixing Xu, Dawei Liu, Fang Xiao, Donghua Zheng


Background: To clarify the key points of cooperation in bedside TCD examination of potential brain death patients and ensure the successful implementation of bedside TCD.

Methods: From June 2018 to May 2019, the clinical data of potential brain death patients, admitted in ICU of the First Affiliated Hospital of Sun Yat-sen University, were prospectively collected; for patients undergoing bedside TCD examination, through cooperating with TCD examination doctors, the related key points were summarized and analyzed.

Results: Among 127 patients entered the study, including 103 males and 24 females, mean age is (33.2±15.2) years. 112 cases (88.2%) successfully implemented bedside TCD, 15 cases (11.8%) failed to implement bedside TCD. Univariate and multivariate analysis showed that: reasonable blood pressure regulation (systolic pressure: 90-140mmhg) (or = 6.58, 95% CI: 1.72-31.69), effective CCA compression test (rapid and accurate compression) (or = 13.62, 95% CI: 3.04-78.93) and body position adjustment (back and bed surface angle: 30-60°) (or = 11.76, 95% CI: 1 49-76.28) is the key points of cooperation for the successful implementation of bedside TCD in potential brain death patients.

Conclusions: The targeted cooperation can ensure the successful implementation of bedside TCD judgment of brain death, and the results need further external validation.


Bedside, Brain death, Cooperation, Intensive care unit, Transcranial doppler

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