DOI: http://dx.doi.org/10.18203/2349-3933.ijam20204533

Multiple cerebral aneurysms: a rare presentation in systemic lupus erythematosus

Avtar Singh Dhanju, Deepshikha Singla, K. Thiyagu, Manisha Khubber, Pranjali Batra, Namit Gupta, Praneet Manekar, Upasna Ajmani

Abstract


Systemic lupus erythematosus is a multisystem autoimmune disorder and its complications include cerebral vasculitis and vasculopathy which can be the first manifestation of SLE. Subarachnoid haemorrhage due to rapid aneurysm growth and rupture is a major neurosurgical emergency associated with significant morbidity and mortality. There is need for more rapid diagnosis and aggressive treatment of SLE patients with unruptured aneurysms. Authors report a case of 23 years old female, a newly diagnosed case of SLE complicated by rupture of cerebral aneurysms.


Keywords


Systemic lupus erythematosus, Aneurysms, Subarachnoid haemorrhage, Optic neuropathy, Anterior cerebral artery

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References


Graffeo CS, Tanweer O, Nieves CF, Belmont HM, Izmirly PM, Becske T et al. Rapid aneurysm growth and rupture in systemic lupus erythematosus. Surg neurol Int. 2015;6:9.

Hanly JG. Diagnosis and management of neuropsychiatric SLE. Nat Rev Rheumatol. 2014;10(6):338-47.

Kaell AT, Shetty M, Lee BC, Lockshin MD. The diversity of neurologic events in systemic lupus erythematosus. Prospective clinical and computed tomographic classification of 82 events in 71 patients. Arch Neurol. 1986;43(3):273-6.

Mimori A, Suzuki T, Hashimoto M, Nara H, Yoshio T, Masuyama JI et al. Subarachnoid hemorrhage and systemic lupus erythematosus. Lupus. 2000;9(7):521-6.

Nagayama Y, Kusudo K, Imura H. A case of central nervous system lupus with ruptured cerebral berry aneurysm. Jpn J Med. 1989;28(4):530-3.

Carvallo JB, Brito CC, EstaƱol B, RamosGG. Subarachnoid hemorrhage as a complication of systemic lupus erythematosus. Cerebrovasc Dis. 2007;24(2-3):301-4.

Hinchey JA, Sila CA. Cerebrovascular complications of rheumatic disease. Rheum Dis Clin North Am. 1997;23(2):293-316.

Juvela S, Poussa K, Porras M. Factors affecting formation and growth of intracranial aneurysms: a long-term follow-up study. Stroke. 2001;32(2):485-91.

Crompton MR. Mechanism of growth and rupture in cerebral berry aneurysms. Br Med J. 1966;1 (5496):1138-42.

Koffijberg H, Buskens E, Algra A, Wermer MJ, Rinkel GJ. Growth rates of intracranial aneurysms: exploring constancy. J Neurosurg. 2008;109(2):176-85.