A case report on Hashimoto’s encephalopathy: an autoimmune neuroendocrine disorder

Abarna Lakshmi R., Rajganesh Ravichandran, Jaya Shree D., Raveena P. B., Nikhil Cherian Sam, Vishnupriya Sarangan


Hashimoto’s encephalopathy (HE) is a rare neuroendocrine disorder with high titers of the thyroid antibodies. HE is more common to women than in men with a ratio of approximately 5:1. The estimated prevalence of HE was 2 per 100,000 people. We present a case of Hashimoto’s encephalopathy in a 24-year-old male patient known case of hypothyroidism admitted with the complaints of unconsciousness, and further developed seizure during admission. Brain magnetic resonance imaging (MRI) was normal, electroencephalogram (EEG) revealed slow diffusion, and the serum thyroid function test showed a high concentration of anti-thyroid antibodies. The patient had a good recovery after the management with steroid therapy.  


Hashimoto’s encephalopathy, Anti-thyroglobulin, Anti-TPO antibodies, Steroid-responsive

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