DOI: http://dx.doi.org/10.18203/2349-3933.ijam20211047

A cross sectional study of acute myocardial infarction in young individuals below 40 years and associated risk factors in Mandya institute of medical sciences, Mandya, Karnataka

Chandregowda ., Mahesh K., Anagha Unnikrishnan

Abstract


Background: Acute coronary syndrome (ACS) is a potentially life‑threatening condition which is more common in elderly people, and young are relatively protected. Its incidence in young Indians is about 12-16%. Currently, the protective effect on young from coronary artery disease (CAD) is taken away by several risk factors. The aim of this study is to determine the conventional and new emerging risk factors like hyperhomocysteinemia and lipoprotein a (Lp [a]) which are suggested to play an important role in myocardial infarction (MI).

Methods: This study was a hospital‑based retrospective cross‑sectional analytical study involving 61 patients aged ≤40years presented with signs and symptoms of ACS confirmed by ECG changes and cardiac enzyme levels admitted in the cardiac ICU from April 2019 to March 2020.

Results: Although ACS is a less common entity in young adults aged ≤40 years, smoking was the most common cause of the MI (75%) in young adults. Homocysteine and Lp (a) should be measured in young MI patients. Smoking cessation and prevention of diabetes and hypertension (HTN) should be encouraged.

Conclusions: Smoking was the most common cause of the MI (75%) in young adults and is the major modifiable risk factor for MI in very young patients which needs strict prevention. Young patients with CAD were mainly males. There is a need for early detection of a risk factor to prevent the progression of ACS,


Keywords


Acute coronary syndrome, Coronary artery disease, Myocardial infarction, Lipoprotein

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References


Rissam H, Kishore S, Trehan N. Coronary artery disease in young Indians-the missing link. J Indian Acad Clin Med. 2001;2(3):128-31.

Singh SS, Paul SK, Pal R, Thatkar PV. Acute coronary syndrome-related mortality audit in a teaching hospital at Port Blair, India. J Family Med Prim Care. 2017;6:502-8.

Iragavarapu T, Radhakrishna T, Babu KJ, Sanghamitra R. Acute coronary syndrome in young-A tertiary care centre experience with reference to coronary angiogram. J Pract Cardiovasc Sci. 2019;5:18-25.

Shah N, Kelly AM, Cox N, Wong C, Soon K. Myocardial Infarction in the "Young": Risk Factors, Presentation, Management and Prognosis. Heart Lung Circ. 2016;25(10):955-60.

Gupta MD, Girish M, Kategari A. Epidemiological profile and management patterns of acute myocardial infarction in very young patients from a tertiary care centre. Indian Heart J. 2020;72(1):32-9.

Bhandari M, Singh V, Venkatraman D. A study of risk factors for acute myocardial infarction in patients below 35 years in eastern India. Nig J Cardiol. 2017;14:84-91.

Sricharan KN, Rajesh S, Rashmi K, Meghana HC, Badiger S, Mathew S. Study of acute myocardial infarction in young adults: Risk factors, presentation and angiographic findings. J Clin Diagn Res. 2012;6:257-60.

Bhardwaj R, Kandoria A, Sharma R. Myocardial infarction in young adults - Risk factors and pattern of coronary artery involvement. Niger Med J. 2014;55(1):44-7.

Pramod MP, Surekha MP, Milind HS. Acute Myocardial Infarction among Young Adults in India: Clinical Profile and Risk Factors. Int J Inno Res Med Sci. 2017;1(09):366-71.

Chandra S, Jain PK. Myocardial Infarction in Young Indian Patients Risk Factors Analysis. J Med Sci clin Res. 2018;6(4):1054-62.

Nagamalesh UM, Abhinay T, Karthik Naidu KC, Ambujam N, Hegde AV, Prakash VS. Clinical profile of young Indian women presenting with acute coronary syndrome. J Clin Prev Cardiol. 2018;7(3):106-10.

Ramesh N, Ganesan K. A study on serum homocysteine as an independent risk factor for coronary artery disease. IAIM. 2019;6(6):75-80.