Published: 2017-02-09

A study of transfusion related adverse events at a tertiary care centre in North India: an initiative towards hemovigilance

Meena Sidhu, Renu Meenia, Irm Yasmeen, Naveen Akhtar


Background: The goal of hemovigilance is to improve the transfusion safety. The present study was undertaken to detect and analyze the transfusion related adverse events as a pilot effort towards hemovigilance from the institution.

Methods: The present retrospective study was conducted in the Department of Transfusion Medicine, Government Medical College, Jammu from Jan 2014- Dec 2014. All the adverse events related to transfusion of blood and blood products reported to the department were recorded and analyzed as per Departmental Standard operating procedures.

Results: During 1 year study period 33,852 blood and blood components were issued to various clinical departments. Ninety four reactions were reported, the type of reaction observed were allergic reactions in 41.5%, followed by febrile non hemolytic transfusion reaction(FNHTR) in 35.5%, Acute hemolytic reactions in 11.7%, delayed hemolytic transfusion reactions(DHTR) in 4.2%, transfusion associated cardiac overload (TACO) in 4.2% and Bacterial sepsis in 2.1%.

Conclusion: The frequency of transfusion in our patients was found to be 0.27%. Factors such as rational use of blood components, improving storage conditions, bedside monitoring of transfusion and documentation of adverse events will help in improving transfusion safety.


Hemovigilance, Transfusion reaction, Adverse events

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