Published: 2017-02-09

Peribronchial inflammatory myofibroblastic tumour: a case report

Easwaramangalath Venugopal Krishnakumar, Ajaykumar ., Augustine Joy, Jaboy Bibin


Inflammatory Myofibroblastic Tumour (IMT) is a rare neoplasm of mesenchymal origin, most commonly seen in the lungs of children and adolescents, but it can occur in older persons also. IMT also called inflammatory pseudotumor accounts for less than 1% of all lung tumours. Approximately half of the patients are asymptomatic. However, the patients with symptoms show cough, haemoptysis, dyspnoea and chest pain. Biopsy by thoracotomy or video assisted thoracoscopic surgery is often necessary to confirm the diagnosis. In this case report, we discuss IMT in a 56-year-old male, who presented with cough and fever of one and a half months duration.


Inflammatory myofibroblastic tumour, Inflammatory pseudotumour, Haemoptysis, Dyspnoea, Fibrosarcoma, Bronchoscopy, Histiocytoma, Xanthogranuloma, Plasmocytoma

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Copin MC, Gosselin BH, Ribet ME. Plasma cell granuloma of the lung: difficulties in diagnosis and prognosis. Ann Thorac Surg. 1996;61:1477-82.

Morar R, Bhayat A, Hammond G, Bruinette H, Feldman C. Inflammatory pseudotumour of the lung: a case report and literature review. Case Rep Radiol. 2012;4:1.

Narla LD, Newman B, Spottswood SS, Narla S, Kolli R. Inflammatory pseudotumor. Radiographics. 2003;23:719-29.

Park SB, Cho KS, Kim JK, Lee JH, Jeong AK, Kwon WJ, et al. Inflammatory pseudotumor (myoblastic tumor) of the genitourinary tract. AJR Am J Roentgenol. 2008;191:1255-62.

Umiker WO, Iverson L. Post inflammatory tumors of the lung; report of four cases simulating xanthoma, fibroma, or plasma cell tumor. J Thorac Surg. 1954;28:55-63.

Cohen MC, Kaschula RO. Primary pulmonary tumors in childhood: a review of 31 years’ experience and the literature. Pediatr Pulmonol. 1992;14:222-32.

Gleason BC, Hornick JL. Inflammatory myofibroblastic tumours: where are we now? J Clin Pathol. 2008;61:428-37.

Maves CK, Johnson JF, Bove K, Malott RL. Gastric inflammatory pseudotumor in children. Radiology. 1989;173:381-3.

Demirhan O, Ozkara S, Yaman M, Kaynak K. A rare benign tumor of the lung: Inflammatory myofibroblastic tumor - case report. Respirat Med Case Rep. 2013;8:32-5.

Agrons GA, Rosado-de-Christenson ML, Kirejczyk WM, Conran RM, Stocker JT. Pulmonary inflammatory pseudotumor: radiologic features. Radiology. 1998;206:511-8.

Huellner MW, Schwizer B, Burger I, Fengels I, Schläpfer R, Bussmann C, et al. Inflammatory pseudotumor of the lung with high FDG uptake. Clin Nucl Med. 2010;35:722-3.

Cerfolio RJ, Allen MS, Nascimento AG, Deschamps C, Trastek VF, Miller DL, et al. Inflammatory pseudotumors of the lung. Ann Thorac Surg. 1999;67:933e6.

Matsubara O, Tan-Liu NS, Kenney RM, Mark EJ. Inflammatory pseudotumors of the lung: progression from organizing pneumonia to fibrous histiocytoma or to plasma cell granuloma in 32 cases. Hum Pathol. 1988;19:807e14.

Hedlund GL, Navoy JF, Galliani CA, Johnson WH Jr. Aggressive manifestations of inflammatory pulmonary pseudotumor in children. Pediatr Radiol. 1999;29:112-6.