DOI: https://dx.doi.org/10.18203/2349-3933.ijam20222958
Published: 2022-11-23

Granulicatella adiacens infective endocarditis

Arun Kumar Alagesan, Tirumalasetty Sriharsha, Raghav J., Vikrannth V., Kannan R., Meenakshi K.

Abstract


Infective endocarditis is an unconventional infectious disease nonetheless life-threatening. A roundabout of 3% to 5% cases of Streptococcal infective endocarditis is caused by nutritionally variant Streptococci (NVS). Granulicatella species is one of the atypical causes of infective endocarditis. In this context, the authors are disclosing a case of infective endocarditis in an underlying rheumatic heart disease patient, caused by Granulicatella adiacens. The patient had breathlessness for the past four months, on and off fever for two months anew and mid-diastolic murmur with vegetation in aortic valve as appeared by echocardiogram. The blood cultures were tested positive for Granulicatella adiacens. The patient was successfully treated with intravenous vancomycin for a period of six weeks. 


Keywords


Granulicatella adiacens, Rare organism, Life threatening

Full Text:

PDF

References


Giuliano S, Caccese R, Carfagna P, Vena A, Falcone M, Venditti M. Endocarditis caused by nutritionally variant streptococci: a case report and literature review. Infez Med. 2012;20:67-74.

Collins MD, Lawson PA. The genus Abiotrophia is not monophyletic: proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov, Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov. Int J Syst Evol Microbiol. 2000;50:365-9.

Stein DS, Nelson KE. Endocarditis due to nutritionally deficient streptococci: therapeutic dilemma. Rev Infect Dis. 1987;9:908.

Casalta JP, Habib G , La Scola B. Molecular diagnosis of Granulicatella elegans on the cardiac valve of a patient with culture-negative endocarditis. J Clin Microbiol. 2002;40:1845-7.

Correa de Sa DD, Tleyjeh IM, Anavekar NS, Schultz JC, Thomas JM, Lahr BD. Epidemiological trends of infective endocarditis: a population-based study in Olmsted County, Minnesota. Mayo Clin Proc. 2010;85(5):422-6.

Heart valves and infective endocarditis. Available at: http://www.heart.org/HEARTORG/Conditions/More/HeartValveProblemsandDisease/Heart-Valves-andInfectiveEndocarditis_UCM_450448_Article.jsp#.WqdwwnzhXIW. Accessed on 20 November 2021.

Thuny F. Diagnostic criteria for infective endocarditis. In: Infective Endocarditis. USA: Springer; 2016:81-6.

Lin C-H, Hsu R-B. Infective endocarditis caused by nutritionally variant streptococci. Am J Med Sci. 2007;334(4):235-9.

Padmaja K, Lakshmi V, Subramanian S, Neeraja M, Krishna SR, Satish OS. Infective endocarditis due to Granulicatella adiacens: a case report and review. J Infect Dev Ctries. 2014;8(4):23-8.

Ruoff KL. Nutritionally variant streptococci. Clin Microbiol Rev. 1991;4:184-90.

Ohara-Nemoto Y, Kishi K, Satho M. Infective endocarditis caused by Granulicatella elegans originating in the oral cavity. J Clin Microbiol. 2005; 43:1405-7.

Adam EL, Siciliano RF, Gualandro DM. Case series of infective endocarditis caused by Granulicatella species. Int J Infect Dis 2015;31:56-8.

Shailaja TS, Sathiavathy KA, Unni G. Infective endocarditis caused by Granulicatella adiacens. Indian Heart J. 2013;65:447-9.

Wilson W, Taubert KA, Gewitz M. Prevention of infective endocarditis: guidelines from the American heart association: rheumatic fever, endocarditis and kawasaki disease committee, council on cardiovascular disease in the young, and the council on clinical cardiology, council on cardiovascular surgery and anesthesia, and the quality of care and outcomes research interdisciplinary working group. J Am Dent Assoc. 2008;139:24.