Published: 2017-05-23

A case of classical sweet syndrome with episcleritis

Hanock Unni Samuel, N. K. Thulaseedharan


Sweet's syndrome (acute febrile neutrophilic dermatosis) is characterized by a constellation of clinical symptoms, physical features, and pathologic findings which include fever, neutrophilia, tender erythematous skin lesions (papules, nodules, and plaques), and a diffuse infiltrate consisting predominantly of mature neutrophils that is typically located in the upper dermis. Sweet's syndrome presents in three clinical settings: classical (or idiopathic), malignancy-associated, and drug-induced. Classical Sweet's syndrome (CSS) usually presents in women between the age of 30 to 50 years, is often preceded by an upper respiratory tract infection and may be associated with inflammatory bowel disease and pregnancy. We report here a case of classical sweets syndrome with the typical histopathological findings who reported well to treatment.


Classical, Episcleritis, Neutrophilic dermal infiltrate, Sweets syndrome

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Von den Driesch P. Sweet's syndrome (acute febrile neutrophilic dermatosis). J Am Acad Dermatol. 1994;31(4):535-56.

Su WP, Liu HN. Diagnostic criteria for Sweet's syndrome. Cutis. 1986;37(3):167-74.

Gottlieb CC, Mishra A, Belliveau D, Green P, Heathcote JG. Ocular involvement in acute febrile neutrophilic dermatosis (Sweet syndrome): new cases and review of the literature. Survey of ophthalmology. 2008;53(3):219-26.

Billings SD, Cotton J. Nodular and diffuse dermatitis. Inflamm Dermatopathol. Springer US; 2010:119-132.

Cohen PR, Kurzrock R. Sweet's syndrome: a review of current treatment options. Am J Clin Dermatol. 2001;3(2):117-31.